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This narrative review is part of a series that will outline the pathophysiology of pyrogenic and non-pyrogenic fever, concentrating primarily on the pathophysiology of non-septic causes.

Hyperthermia also has no agreed definition; it has been defined as a core temperature above Common causes include classical and exertional heatstroke, and drug-related illnesses for example, malignant hyperthermia and neuroleptic syndrome. There is, however, increasing evidence that many conditions considered non-pyrogenic may stimulate an inflammatory response, and the division into pyrogenic and non-pyrogenic may therefore be less clear-cut than previously understood.


Neurogenic fever, and fevers associated with endocrinopathy, are rarer. Sepsis Pyrogenic fever is a common response to sepsis in critically ill patients, and the generation of fever occurs through several mechanisms. The interaction of exogenous pyrogens e.

Exogenous pyrogens may stimulate cytokine production, or may act directly on the OVLT.Epub Jan 8 Moringa oleifera Lam. In addition, the patient may develop other symptoms such as cerebral malaria, generalized convulsions, severe anemia, hypoglycemia, acidosis, high fever, jaundice and hyper-parasitemia 4 , 5 , 6 , 7.

The book has been awarded with , and many others. The incidence, severity and distribution of malaria is also affected substantially by human activities such water and agricultural developments and by urbanization. Anti-inflammatory and antioxidant effects of a combination of cannabidiol and moringin in LPS-stimulated macrophages.

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TROY from Redding
I do love reading novels knottily. Browse my other articles. I have always been a very creative person and find it relaxing to indulge in padiddling.